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. Author manuscript; available in PMC: 2018 Jun 1.
Published in final edited form as: Bioorg Med Chem. 2017 Mar 27;25(11):2926–2931. doi: 10.1016/j.bmc.2017.03.035

Figure 3.

Figure 3

Toxicity analysis of aryl isonitrile compounds against human epithelial colorectal cells (HRT-18). Percent viable mammalian cells (measured as average absorbance ratio (test agent relative to DMSO)) for cytotoxicity analysis of compounds (tested in triplicate) at 128 and 256 μM against HRT-18 cells using the MTS assay. Dimethyl sulfoxide (DMSO) served as a negative control to determine a baseline measurement for the cytotoxic impact of each compound. The absorbance values represent an average of a minimum of three samples analyzed for each compound. Error bars represent standard deviation values for the absorbance values. A two-way ANOVA, with post hoc Dunnet's multiple comparisons test, determined no statistical difference between the values obtained for each compound and DMSO (P < 0.05).