Table 2. The minimum inhibitory concentration (MIC in μM) of synthesized compounds and fluconazole screened against clinical isolates of Candida albicans and non-albicans Candida species.
| Compound/Drug Name | |||||||
|---|---|---|---|---|---|---|---|
| Strain Name | 2 | 22 | 23 | 25 | 26 | 32 | Fluconazole |
|
Candida albicans ATCC 29351 |
1 | 1 | 2 | 1 | ≤0.5 | ≤0.5 | ≤0.5 |
|
Candida albicans ATCC 27365 |
1 | 1 | 2 | 2 | 1 | ≤0.5 | 1 |
|
Candida albicans NR-29368 |
2 | ≤0.5 | 4 | 2 | 2 | 8 | >64 |
|
Candida albicans NR-29446 |
1 | ≤0.5 | 1 | 2 | 2 | 8 | >64 |
|
Candida albicans ATCC MYA 573 |
1 | ≤0.5 | 1 | 2 | 2 | 16 | >64 |
|
Candida albicans ATCC 64124 |
2 | ≤0.5 | 2 | 2 | 2 | 64 | >64 |
|
Candida krusei ATCC 14243 |
32 | 4 | 32 | 64 | 32 | >64 | 64 |
|
Candida krusei ATCC 34135 |
16 | 2 | 16 | 32 | 8 | >64 | 64 |
|
Candida parapsilosis ATCC 22019 |
2 | 4 | 8 | 4 | 1 | ≤0.5 | 1 |
|
Candida glabrata ATCC MYA-2950 |
8 | 16 | 8 | 8 | ≤0.5 | ≤0.5 | >64 |
|
Candida glabrata ATCC 66032 |
8 | 16 | 8 | 4 | 1 | 1 | >64 |
|
Candida tropicalis ATCC 1369 |
16 | 16 | 8 | 2 | 2 | 1 | >64 |
|
Candida tropicalis ATCC 13803 |
4 | 4 | 8 | 4 | 1 | ≤0.5 | >64 |