Table 3.
Uni- and multivariate analyses of TLR9 rs5743836 polymorphism in unprovoked recurrent VTE patients
| Genotypes | All unprovoked VTE patients | Unprovoked women | ||||||
|---|---|---|---|---|---|---|---|---|
| Univariate HR (95% CI) | P | Multivariate HR (95% CI) | P* | Univariate HR (95% CI) | P | Multivariate HR (95% CI) | P* | |
| rs5743836 | ||||||||
| TT | Reference | Reference | Reference | Reference | ||||
| TC | 0.91 (0.54–1.53) | 0.723 | 0.92 (0.54–1.56) | 0.746 | 1.27 (0.61–2.63) | 0.519 | 1.13 (0.53–2.42) | 0.756 |
| CC | 0.65 (0.16–2.67) | 0.553 | 0.60 (0.14–2.46) | 0.474 | 3.79 (0.89–16.04) | 0.071 | 5.94 (1.25–28.13) | 0.025 |
| TT&TC | Reference | Reference | Reference | Reference | ||||
| CC | 0.67 (0.16–2.72) | 0.573 | 0.61 (0.15–2.50) | 0.491 | 3.57 (0.86–14.94) | 0.081 | 5.79 (1.23–27.19) | 0.026 |
significant P-values are shown in bold letters
*P adjusted for family history of VTE, mild and severe thrombophilia and location of VTE