Table 1.
Patient and biochemical variables during follow-up. The reference ranges are marked in parentheses; the reference ranges which have changed during follow-up are marked with an asterisk
| 1993 | 1994 | 1996 | 2000 | 2016 | |
|---|---|---|---|---|---|
| Height, cm | 172 | 172 | 171 | 170 | 169 |
| Body weight, kg | 60 | 59 | 61 | 60 | 62 |
| BMI, kg/m2 | 20.3 | 19.9 | 20.9 | 20.8 | 21.7 |
| Levothyroxine, average daily dose (μg) | 300 | 125 | 100 | 112.5 | 107 |
| Free T4, pmol/L (10–22) | 37 | 15 | 15 | 12 | 24 |
| T3, nmol/L (1.3–3.1) | 2.6 | 2.4 | 1.6 | ||
| TSH, mU/L (0.2–4.2) | 0.0001 | 0.015 | 0.03 | 0.28 | 0.06 |
| Osteocalcin, μg/L (3.0–7.5)(5.4–59)* | 9.6 | 6.8 | 7.0 | 6.0 | 19* |
| PTH, ng/L (10–64)(1.6–6.9 pmol/L)* | 31.8 | 41.2 | 53 | 3.77* | |
| Calcium, mmol/L (2.15–2.5) | 2.39 | 2.37 | 2.36 | 2.34 | 2.5 |
| Ionized calcium, mmol/L(1.18–1.31) | 1.30 | 1.27 | 1.21 | 1.23 |