Table 4.
Prognostic factors on uni- and multivariate Cox regression analysis for disease-free survival
| HR (95% CI) | P value | |
|---|---|---|
| Univariate analysis | ||
| Group 2 | 1.509 (0.959–2.375) | 0.075 |
| Celiac lymph node metastasis | 3.898 (1.923–7.904) | 0.000 |
| Cardia growth 2–4 cm | 1.454 (0.742–2.849) | 0.275 |
| Length >8 cm | 1.103 (0.580–2.097) | 0.764 |
| Weight loss >10% | 1.229 (0.720–2.096) | 0.450 |
| Female | 0.484 (0.255–0.920) | 0.027 |
| Squamous cell carcinoma | 0.366 (0.167–0.802) | 0.012 |
| cT1 and T2 | 1.000 | 0.084 |
| cT3 | 1.961 (1.003–3.833) | |
| cT4a | 2.894 (0.984–8.510) | |
| ypT0 | 1.000 | 0.023 |
| ypT1 | 1.535 (0.636–3.706) | |
| ypT2 | 3.056 (1.298–7.194) | |
| ypT3 | 2.632 (1.275–5.435) | |
| ypN0 | 1.000 | 0.001 |
| ypN1 | 1.470 (0.812–2.659) | |
| ypN2 | 3.060 (1.618–5.785) | |
| ypN3 | 4.374 (1.682–11.375) | |
| R1 resection | 4.389 (2.043–9.431) | 0.000 |
| LN ratio (>0.2 LN +) | 3.106 (1.758–5.489) | 0.000 |
| Perineural growth | 1.694 (0.993–2.890) | 0.053 |
| Lymphangio-invasion | 1.940 (1.131–3.327) | 0.016 |
| Multivariate analysisa | ||
| Female | 0.474 (0.248–0.907) | 0.024 |
| Squamous cell carcinoma | 0.413 (0.185–0.923) | 0.031 |
| Group 2 | 1.685 (1.061–2.676) | 0.027 |
| LN ratio (>0.2 LN +) | 2.712 (1.524–4.826) | 0.001 |
HR hazard ratio, CI confidence interval, cT clinical T stage, ypT pathologic T stage, ypN pathologic lymph node stage, LN lymph node
PUB1: OK not to spell PET/CT here? Spelling here would be cumbersome
aVariables with P < 0.10 in the univariate analysis were included in the multivariate analysis