Table 3.

HR-pQCT measures in patients and controls

Geometry	Radius			Tibia
	AN (n = 25)	Controls (n = 25)	p value	AN (n = 25)	Controls (n = 25)	p value
Total bone area (mm2)	251.9 ± 51.9	262.9 ± 47.8	0.56	680.7 ± 166.8	669.4 ± 119.2	0.78
Mean perimeter (mm)	66.2 ± 7.2	67.3 ± 6.2	0.56	101.0 ± 11.5	100.5 ± 8.7	0.86
Cortical area (mm2)	46.0 ± 11.6	52.8 ± 11.7	0.06	92.4 ± 21.5	123.1 ± 20.7	<0.0001
Trabecular area (mm2)	203.7 ± 54.9	206.5 ± 49.7	0.86	583.5 ± 177.9	545.2 ± 122.1	0.38
Cortical thickness (mm)	0.71 ± 0.23	0.79 ± 0.20	0.20	0.94 ± 0.29	1.24 ± 0.24	<0.0005
vBMD
Total vBMD (mg/cm3)	284.7 (229.6; 312.9)	298.8 (280.0; 340.1)	0.10	251.3 ± 72.5	320.1 ± 48.7	<0.0005
Cortical vBMD (mg/cm3)	861. ± 78.9	878.4 ± 56.6	0.17	882.5 (866.2; 901.8)	912.2 (903.6; 925.1)	<0.01
Trabecular vBMD, mg/cm3	124.8 ± 35.9	155.7 ± 34.9	<0.005	137.1 ± 38.3	178.7 ± 31.0	<0.0005
Microarchitecture
BV/TV, [1]	0.104 ± 0.030	0.130 ± 0.029	<0.005	0.114 ± 0.032	0.150 ± 0.025	<0.0001
Tb.Th. (mm)	0.063 ± 0.012	0.067 ± 0.012	0.18	0.069 ± 0.012	0.078 ± 0.013	<0.01
Tb.N (1/mm)	1.64 ± 0.27	1.92 ± 0.29	<0.001	1.64 ± 0.26	1.93 ± 0.30	<0.001
Tb.Sp (mm)	0.563 (0.468; 0.625)	0.432 (0.400; 0.490)	<0.001	0.554 ± 0.102	0.4512 ± 0.079	<0.0005
Cortical porosity (%)	0.72 (0.56; 1.15)	0.96 (0.63; 1.09)	0.55	2.65 (1.90; 3.59)	2.71 (2.21; 3.36)	0.70
Estimated strength
Stiffness	61,444 ± 12,520	74,868 ± 13,673	<0.001	162,158 ± 27,161	214,192 ± 33,105	<0.0001
Failure load (N)	3115 ± 612	3810 ± 675	<0.0005	8242 ± 1284	10,727 ± 1624	<0.0001

Values are presented as mean ± SD or median and interquartile range, as appropriate. p values in bold indicates p < 0.05 on difference between groups

AN anorexia nervosa, vBMD volumetric bone mineral density, BV/TV. bone volume/tissue volume, Tb.Th. trabecular thickness, Tb.N. trabecular number, Tb.Sp. trabecular spacing