Table 3. Outcome measure summary statistics and intervention effects at 3, 6, and 12 months.
| Supported cCBT | Guided self-help | Waiting list | Supported cCBT–Waiting list | Guided self-help–Waiting list | Supported cCBT–Guided self-help | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mean | SD | n | Mean | SD | n | Mean | SD | n | Adjusted mean difference + | 95% CI |
p | Adjusted mean difference+ | 95% CI | p | Adjusted mean difference+ | 95% CI |
p | |
| Y-BOCS-OR | ||||||||||||||||||
| Baseline | 25.03 | 5.45 | 157 | 25.01 | 5.02 | 158 | 25.34 | 5.44 | 158 | |||||||||
| 3 months | 21.16 | 6.89 | 121 | 20.19 | 6.83 | 130 | 22.18 | 6.54 | 132 | −0.71 | (−2.12 to 0.70) |
0.325 | −1.91 | (−3.27 to −0.55) | 0.006* | 1.20 | (−0.22 to 2.61) |
0.097 |
| 6 months | 18.96 | 7.26 | 112 | 18.70 | 7.70 | 122 | 20.29 | 7.27 | 122 | −1.13 | (−2.84 to 0.58) |
0.195 | −1.32 | (−3.00 to 0.35) | 0.121 | 0.19 | (−1.51 to 1.90) |
0.824 |
| 12 months | 16.14 | 8.69 | 105 | 15.19 | 8.35 | 113 | 17.93 | 8.07 | 114 | −1.37 | (−3.59 to 0.84) |
0.224 | −2.37 | (−4.37 to −0.38) | 0.020 | 1.00 | (−1.19 to 3.19) |
0.371 |
| Y-BOCS-SR | ||||||||||||||||||
| Baseline | 24.34 | 5.10 | 157 | 24.18 | 4.82 | 158 | 24.20 | 4.99 | 158 | |||||||||
| 3 months | 20.46 | 7.06 | 119 | 19.80 | 6.90 | 128 | 20.88 | 6.48 | 127 | −0.43 | (−1.79 to 0.93) |
0.531 | −1.31 | (−2.65 to 0.04) | 0.056 | 0.87 | (−0.49 to 2.23) |
0.209 |
| 6 months | 18.60 | 7.47 | 110 | 18.29 | 7.78 | 119 | 19.34 | 7.24 | 118 | −0.87 | (−2.52 to 0.78) |
0.300 | −1.17 | (−2.87 to 0.53) | 0.178 | 0.30 | (−1.42 to 2.02) |
0.735 |
| 12 months | 15.61 | 8.70 | 101 | 15.72 | 8.11 | 109 | 17.38 | 8.24 | 107 | −1.45 | (−3.67 to 0.76) |
0.198 | −1.52 | (−3.54 to 0.49) | 0.137 | 0.07 | (−2.01 to 2.16) |
0.946 |
| CSQ-8 | ||||||||||||||||||
| 3 months | 22.41 | 5.91 | 92 | 24.37 | 5.49 | 101 | 22.75 | 6.06 | 83 | −0.31 | (−2.07 to 1.45) |
0.732 | 1.69 | (−0.04 to 3.42) | 0.055 | −2.00 | (−3.63 to −0.37) |
0.016* |
| 6 months | 23.75 | 5.78 | 81 | 24.26 | 6.29 | 82 | 24.64 | 5.80 | 77 | −0.87 | (−2.77 to 1.03) |
0.371 | −0.31 | (−2.23 to 1.61) | 0.751 | −0.56 | (−2.44 to 1.32) |
0.561 |
| EQ-5D | ||||||||||||||||||
| Baseline | 0.67 | 0.29 | 155 | 0.68 | 0.26 | 155 | 0.68 | 0.26 | 154 | |||||||||
| 3 months | 0.69 | 0.31 | 104 | 0.73 | 0.24 | 117 | 0.67 | 0.28 | 124 | 0.03 | (−0.02 to 0.09) |
0.246 | 0.05 | (0.00 to 0.10) | 0.042 | −0.01 | (−0.07 to 0.04) |
0.491 |
| 6 months | 0.71 | 0.29 | 94 | 0.72 | 0.25 | 105 | 0.71 | 0.25 | 106 | 0.00 | (−0.06 to 0.06) |
0.961 | 0.00 | (−0.05 to 0.07) | 0.815 | −0.00 | (−0.07 to 0.06) |
0.864 |
| 12 months | 0.79 | 0.27 | 84 | 0.73 | 0.26 | 100 | 0.70 | 0.31 | 99 | 0.07 | (0.00 to 0.15) | 0.041 | 0.03 | (−0.04 to 0.09) | 0.449 | 0.05 | (−0.02 to 0.12) | 0.179 |
+ Mean difference adjusted for Y-BOCS-OR, PHQ-9, GAD-7, antidepressant use, gender, and OCD duration (0–5, 6–9, and ≥10 years).
* The significance level is set at 1.67% to adjust for 3 pair-wise comparisons.
Abbreviations: CSQ-8, Client Satisfaction Questionnaire; EQ-5D, EuroQol five dimensions questionnaire; GAD-7, Generalised Anxiety Disorder 7-item; OCD, obsessive-compulsive disorder; PHQ-9, Patient Health Questionnaire; Y-BOCS-OR, Yale-Brown Obsessive Compulsive Scale–Observer-Rated; Y-BOCS-SR, Yale-Brown Obsessive Compulsive Scale–Self-Report.