Table 1.
Baseline Demographics and Clinical Characteristics of RA-ILD and IPF Patients
| Variable | RA-ILD (n=50) | IPF (n=50) | P Value |
|---|---|---|---|
| Age, years | 66.7 ± 9.8 | 70.8 ± 8.3 | 0.02 |
| Male sex | 18 (36%) | 39 (78%) | <0.01 |
| BMI* | 28.8 ± 5.6 | 28.1 ± 8.3 | 0.61 |
| Ever smoker | 31 (62%) | 31 (62%) | 1.00 |
| FVC% | 72.0 ± 20.5 | 70.3 ± 18.9 | 0.66 |
| DLCO%† | 51.0 ± 19.2 | 48.5 ± 16.6 | 0.49 |
| Prednisone use at baseline | 45 (90%) | 19 (38%) | <0.01 |
| Diabetes mellitus | 11 (22%) | 7 (14%) | 0.30 |
| Sleep apnea | 10 (20%) | 13 (26%) | 0.48 |
| Fatigue | 41 (82%) | 36 (72%) | 0.24 |
| Cough | 43 (86%) | 44 (88%) | 0.77 |
| Joint pain or stiffness | 46 (92%) | 22 (44%) | <0.01 |
| Weight loss | 18 (36%) | 14 (28%) | 0.39 |
| Heartburn | 23 (46%) | 18 (36%) | 0.31 |
| UCSD SOBQ score¶ | 49.8 ± 29.8 | 50.1 ± 32.4 | 0.96 |
Data are expressed as number (%) for categorical variables and mean ± standard deviation for continuous variables.
*
Body-mass index data missing in 3 RA-ILD patients
†
DLCO% data missing in 1 RA-ILD patient
¶
UCSF SOBQ score data missing in 1 RA-ILD patient; higher scores indicate worse dyspnea
RA-ILD = rheumatoid arthritis-associated interstitial lung disease. IPF = idiopathic pulmonary fibrosis. FVC% = percent predicted forced vital capacity. DLCO% = percent predicted diffusing capacity for carbon monoxide. UCSD SOBQ = University of California, San Diego Shortness of Breath Questionnaire10.