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. 2017 Jun 27;12(6):e0178572. doi: 10.1371/journal.pone.0178572

Table 1. Clinical characteristics of treatment groups.

Variables Whole cohort
N = 20
IVIG+
N = 11
IVIG-
N = 9
P
At the time of transplant
Recipient
Female sex, N (%) 8 (40) 5 (45) 3 (33) 0.50
Age, years, mean (SD), range 47 (± 15) (22–75) 45 (± 17) (28–75) 50 (± 15) (22–63) 0.54
Initial nephropathy, N (%)
  Glomerular 8 (40) 6 (55) 2 (28) 0.31
  Genetic 1 (5) 1 (9) 0 (0)
  Other 11 (55) 4 (45) 6 (66)
Dialysis, N (%) 16 (80) 10 (90) 6 (66) 1.00
  Time, months, median (Q1-Q3) 49 (33–57) 51 (40–61) 42 (21–89) 0.67
Donor
Deceased, N (%) 17 (85) 9 (81) 6 (66) 1.00
Female sex, N (%) 11 (55) 6 (55) 5 (55) 1.00
Age, years, mean (SD) 49 (±16) 52 (±16) 44 (±17) 0.34
eGFR (ml/min/1,73m2), mean (SD) 89 (±36) 81 (±40) 103 (±27) 0.21
Proteinuria (g/l), median (Q1-Q3) 0.14 (0.07–0.47) 0.14 (0.11–0.68) 0.06 (0.04–0.25) 0.04
Cold ischemia time, hours, mean (SD) 18 (±7) 18 (±5) 18 (±11) 0.90
HLA mismatch
 class I, mean (SD) 3 (±1) 3 (±1) 3 (±1) 1.00
 class II, mean (SD) 2 (±1) 2 (±1) 3 (±1) 0.23
Anti-HLA antibodies, N (%) 8 (40) 5 (45) 3 (33) 0.32
  Donor specific antibodies, N (%) 0 (0) 0 (0) 0 (0) .
Immunosuppression
Induction, N (%) 20 (100) 11 (100) 9 (100) 1.00
  Anti-thymocyte globulin, N (%) 11 (55) 7 (64) 4 (43) 0.63
  Interleukin-2 receptor antibody, N (%) 9 (45) 4 (36) 5 (57)
Post-transplant
Maintenance therapy
  Steroids, N (%) 20 (100) 11 (100) 9 (100) 0.65
  Calcineurin inhibitors, N (%) 20 (100) 11 (100) 9 (100)
   Cyclosporine, N (%) 9 (45) 4 (36) 5 (55)
   Tacrolimus, N (%) 11 (55) 7 (64) 4 (44)
  Mycophenolate mofetil, N (%) 20 (100) 11 (100) 9(100)
Infectious diseases, N (%)
  CMV viremia, N (%) 2 (10) 2 (18) 0 (0) 0.49
   Before IVIG, N (%) . 1 (50) .
  BK virus viremia, N (%) 2 (10) 1 (9) 1 (11) 1.00
   Before IVIG, N (%) . 1 (100) .
Last follow-up
 eGFR, ml/min/1.73m2, mean (SD) 56 (±22) 58 (±25) 53 (±20) 0.60
 Allograft loss, N (%) 0 (0) 0 (0) 0 (0) .
 Death, N (%) 0 (0) 0 (0) 0 (0) .