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. 2017 Jun 27;12(6):e0179692. doi: 10.1371/journal.pone.0179692

Fig 1. The lipogenic phenotype reprograms the epigenome in Ut-LMS.

Fig 1

Enhanced lipogenesis modifies the epigenome to transform mesenchymal cells in Ut-LMS. Akt, protein kinase B; mTORC1, mammalian target of rapamycin complex 1; FA, fatty acid; FASN, fatty acid synthase; SREBP-1c, sterol regulatory element-binding protein-1c; Ut-LMS, uterine leiomyosarcoma.