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Role of survivin in MLS cell lines. Dose-response curves for YM155 (72 hours) in MLS cell lines. Error bars represents three experiments performed in triplicates (A). Normalized RNA expression of three survivin isoforms in cell lines showing relative abundance of the Δex3 isoform (B). Survivin immunohistochemistry of FFPE cell pellets revealed a strong nuclear survivin expression in the cell lines 402-91 (C), 1765-92 (D), and DL-221 (E) (20× magnification).
