Table 6.

Performance of kidney solid organ response test in the acute rejection in renal transplantation AART143, AART124, and AART100 cohorts

kSORT predictions
	AART143 (training set)		AART124 (validation set)		AART100 (cross-validation set)
	AR	No AR	AR	No AR	AR	No AR
Real results						3
AR	39	8	21	2	36	43
No AR	9	87	1	100	3
Sensitivity (95%CI)	82.98% (69.19%-92.35%)		91.30% (71.96%-98.38%)		92.31% (79.13%-98.38%)
Specificity (95%CI)	90.63% (82.95%-95.62%)		99.01% (94.61%-99.97%)		93.48% (82.1%-96.63%)
PPV (95%CI)	81.25% (68.06%-89.81%)		95.46% (78.20%-99.19%)		93.21% (79.68%-97.35%)
NPV (95%CI)	91.58% (84.25%-95.67%)		98.04% (93.13%-99.46%)		93.48% (82.45%-97.76%)
AUC (95%CI)	0.94 (0.91-0.98)		0.95 (0.88-1.00)		0.92 (0.86-0.98)

kSORT: Kidney solid organ response test; AART: Assessment of acute rejection in renal transplantation; AR: Acute rejection; PPV: Positive predictive value; NPV: Negative predictive value; AUC: Area under the curve.