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. 2017 Jun 27;7:4287. doi: 10.1038/s41598-017-04642-4

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Copy number variations in KOVA. (a) Distribution of KOVA CNV sizes. (b) Frequency of CNVs by number of events in KOVA. (c) Highly polymorphic copy number genes in KOVA. Genes are sorted by frequency. (d) Copy number genotype profiles of SIGLEC14 and SIGLEC5. (e) Frequency of SIGLEC14 deletion allele in worldwide populations from DGV. AFR: African, AMR: Mexican, native American, North American, and South American, ASN: Asian, EUR: European.