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. Author manuscript; available in PMC: 2017 Jun 28.
Published in final edited form as: Chem Rev. 2017 Apr 17;117(11):7276–7330. doi: 10.1021/acs.chemrev.6b00729

Figure 28.

Figure 28

Sampling rates and “connect-the-dots” schemes can bias interpretation. Consider two particles that are undergoing oscillatory motion with the same amplitude and frequency but are slightly off-phase (top and middle, blue curves). At a frame rate less than the period of the particle motion, observations (top and middle, yellow curves) suggest an oscillatory model with the same amplitude but a different frequency. This effect, where some motion characteristics are inferred correctly while others are not, is called “aliasing” and is a key challenge of temporal super-resolution.