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. 2017 Jun 28;8:1171. doi: 10.3389/fmicb.2017.01171

Figure 3.

Figure 3

CRM1-inhibition by Leptomycin B. Leptomycin B binds to CRM1 at Cys528 residing in its NES-binding groove and inhibits the binding of the cargo to CRM1.