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MultiEPSP-dependent SCRs in SNpc DAergic neurons are mainly mediated by L-type calcium channels. SCRs were tested with the T- and L-type calcium channels’ antagonists mibefradil and isradipine (5 μM, each). Both drugs are able to reduce SCRs, but only in the case of isradipine the effect achieved statistical significance. No effect of T- and L-type calcium channels block was seen on multiEPSP (left, black traces).
