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Chloramphenicol is produced constitutively and at higher levels in the absence of MtrB. Levels of chloramphenicol detected in wild-type S. venezuelae NRRL B-65442 (blue) and the isogenic ΔmtrB mutant (red). Note that chloramphenicol is only produced following sporulation in the wild-type but is produced at all stages of growth and at higher levels in the ΔmtrB mutant. All measurements were on biological and technical triplicate samples.
