Table 1.

The main timeline of eRNA studies

Year	Brief description and significance	Refs.
1990, 1992	The early studies demonstrating that transcripts can be produced from enhancer regions	[20], [21]
2010	The first paper proposing the notion of eRNAs	[16]
2010, 2012	Genome-wide analysis suggesting that enhancers may be generally transcribed	[17], [18]
2013, 2014	Increasing evidence showing that eRNAs play an important role in regulating gene transcription via diverse mechanisms	[22], [23], [24], [25], [26], [27]
2014	In vivo study confirming that many eRNAs are expressed in a tissue-specific manner	[28]
2014	Study revealing a comprehensive transcriptomic profiling of eRNAs in humans	[29]
2015	Study illuminating the role of RNA exosome in controlling eRNA degradation	[30]
2016	Study showing that some eRNAs marked with m5C are responsible for metabolic stress	[31]

Note: This collection does not contain all the studies on eRNAs and only some representative articles are listed.