TABLE 2.
In silico prediction of CD8+ T cell epitopes in peptides p51 and p52 in CB6F1 micea
Peptideb | Epitope sequence | Allele | MHC IC50 (nM) |
---|---|---|---|
p51 | SVRLRAYL | H-2b | 344.7 |
p51 | WYELTPAETSV | H-2d | 537.7 |
p52 | RAYLNTPGL | H-2b | 68.8 |
p52 | AYLNTPGL | H-2d | 122.0 |
In silico prediction of strong CD8+ T cell epitopes defined by their 50% inhibitory concentration (IC50) values were computed for H-2b and H-2d backgrounds by use of the IEDB Analysis Resource NetMHCpan algorithm.
Peptide sequences were as follows (identical residues are in italics): p51, WYELTPAETSVRLRAYLNTP; p52, VRLRAYLNTPGLPVCQDHLE.