FIG 1.

Cross-sectional analysis of CD4 T and B cells isolated from HIV progressors, HIV viremic controllers, HIV elite controllers, and HIV-uninfected individuals. (A) Comparison of absolute numbers of CD4 T cell counts. (B) Frequency of CXCR5⁺ CD4⁺ T cells. (C) Frequencies of B cell subpopulations. Memory B cell subgroups in CD19⁺ IgD⁻ CD27^+/− B cells were identified as CD21⁻ CD27⁺ activated memory (AM), CD21⁺ CD27⁺ resting memory (RM), CD21⁻ CD27⁻ tissue-like memory (TLM), and CD21⁺ CD27⁻ intermediate memory (IM). (D) Comparison of B cell subpopulation frequencies in each subgroup. Bars represent means ± SEM and groups compared by Mann-Whitney tests. For all graphs, colors of symbols represent HIV progressors (orange), HIV viremic controllers (blue), HIV elite controllers (green), and HIV-uninfected individuals (purple).