Table 2.

Results using probit modelling: risk factor effects (OR and 95% CIs) on depression and PEs at 12 and 18 years (N = 7058), respectively and averaged over 100 imputations for missing data, as described in “Methods”

	Age	DSs*		PEs*		Wald tests
						DSs	PEs	Common effect t stat. (p val.)
		OR	95% CI	OR	95% CI	Time effects t stat. (p val.)a	Time effect t stat. (p val.)b	12 years 18 yearsc
Socio-demographic
Female	12	1.58	[1.36 1.84]	1.14	[1.00 1.29]	−3.03 (0.002)	−1.64 (0.102)	3.60 (<0.0001)
	18	2.14	[1.85 2.47]	1.32	[1.13 1.54]			4.81 (<0.0001)
Marital status unmarried	12	1.22	[0.98 1.51]	1.32	[1.11 1.56]	−0.62 (0.534)	−2.02 (0.043)	−0.64 (0.525)
	18	1.33	[1.10 1.60]	1.69	[1.37 2.08]			−1.88 (0.060)
Low maternal education	12	1.07	[0.92 1.25]	1.19	[1.04 1.35]	0.07 (0.946)	−1.78 (0.076)	−1.12 (0.263)
	18	1.07	[0.93 1.23]	1.41	[1.20 1.66]			−2.83 (0.005)
Main risk factors
LoC externality (time-varying)	12	1.15	[1.05 1.25]	1.26	[1.18 1.36]	−3.42 (0.001)	−1.72 (0.087)	−1.93 (0.054)
	18	1.41	[1.29 1.53]	1.41	[1.26 1.58]
Social communication (time-varying)	12	1.21	[1.10 1.33]	1.08	[1.00 1.17]	0.32 (0.751)	−0.6 (0.546)	1.86 (0.064)
	18	1.19	[1.08 1.30]	1.13	[1.01 1.26]			0.78 (0.433)
DANVA 8 years	12	0.96	[0.89 1.04]	0.92	[0.86 1.00]	0.49 (0.623)	−1.33 (0.184)	0.8 (0.426)
	18	0.94	[0.88 1.01]	0.99	[0.91 1.07]			−1.01 (0.311)
Emotional triangles	12
	18	1.07	[1.00 1.14]	1.05	[0.97 1.13]			0.34 (0.731)
Confounders
IQ	12	0.90	[0.83 0.97]	0.86	[0.80 0.92]	−1.81 (0.071)	−0.85 (0.398)	0.92 (0.359)
	18	0.98	[0.91 1.06]	0.89	[0.82 0.97]			1.92 (0.055)
Autistic traits	12	1.08	[1.00 1.17]	1.12	[1.05 1.20]	0.72 (0.469)	−0.55 (0.583)	−0.84 (0.401)
	18	1.04	[0.97 1.12]	1.15	[1.07 1.25]			−2.07 (0.039)

*Analysis scale is expressed in the standard deviation units, where the scale is transformed to have a mean 0 and SD = 1

^aTest of evidence against the null hypothesis that the strength of the association between risk factors and depression modelled separately at each timepoint is equal to the strength of the association between risk factors and depression modelled across timepoints

^bTest of evidence against the null hypothesis that the strength of the association between risk factors and psychotic experiences modelled separately at each timepoint is equal to the strength of the association between risk factors and psychotic experiences modelled across timepoints

^cTest of evidence against the null hypothesis that the strength of the association between risk factors and the psychopathologies modelled separately at each timepoint is equal to the strength of the association between the risk factors and both psychopathologies modelled together at each timepoint