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Reversion of resistant phenotype by inhibition with LdAPx inhibitors as shown by an in vitro AmB sensitivity assay
| Treatment group | AmB LD50 (μg/ml) | Fold change |
|---|---|---|
| Sensitive + AmB | 0.12 | |
| Resistant + AmB | 0.83 | |
| Resistant + I1 + AmB | 0.42 | ∼2.0 |
| Resistant + I2 + AmB | 0.45 | ∼1.85 |
| Resistant + I3 + AmB | 0.63 | ∼1.25 |
