TABLE 1.
Antimicrobial susceptibility profiles of Pseudomonas putida isolates DZ-C20, DZ-C18, and DZ-F23; Pseudomonas aeruginosa DZ-B1; and recombinant E. coli strains HSG398-V01 and HSG398-DH5α
| Bacterial isolate | Resistance gene(s) | MIC (mg/liter) ofa: |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| MEM | IMI | ATM | CAZ | GEN | CIP | COL | TGC | TMP | ||
| DZ-C18 | blaCARB-4, blaVIM48, strA, strB, aacA4, aadA13, QnrVC1, mph(A), cmlA1, floR, tet(A), tet(G), sul1 | 128 | 128 | 256 | 128 | 64 | 32 | 2 | 8 | ≥256 |
| DZ-C20 | blaCARB-4, blaVIM-48, strA, strB, aacA4, aphA6, QnrVC1, mph(A), floR, catB, tet(G), sul1 | 64 | 32 | 128 | 128 | 128 | 32 | 4 | 2 | ≥256 |
| DZ-F23 | blaCARB-4, blaVIM-48, strA, strB, aacA4, aphA6, QnrVC1, mph(A), floR, tet(G), sul1 | 64 | 32 | 32 | 32 | 16 | 32 | 1 | 8 | ≥256 |
| DZ-B1 | blaVIM-2, blaOXA-50, ampC, strA, strB, aacA4, aph(3′)-IIa, aph(3′)-IIb, aac(6′)-IIa, catB7, floR, tet(G), sul1, dfrB1, fosA | 32 | 32 | 4 | 64 | 256 | 256 | 2 | 8 | ≥256 |
| HSG398-V01 | blaVIM-48 | 0.125 | 1 | 0.032 | 2 | |||||
| HSG398-DH5α | 0.0625 | 0.25 | 0.032 | 0.125 | ||||||
a
Antimicrobial agents are abbreviated as follows: MEM, meropenem; IMI, imipenem; ATM, aztreonam; CAZ, ceftazidime; GEN, gentamicin; CIP, ciprofloxacin; COL, colistin; TGC, tigecycline; TMP, trimethoprim.