TABLE 3.
Antifungal susceptibilities of C. guilliermondii complex and C. albicans isolates from the CANDIPOP studya
| Antifungal |
C. guilliermondii complex biofilm SMIC50 (μg/ml) |
MIC (μg/ml) |
|||||||
|---|---|---|---|---|---|---|---|---|---|
|
C. guilliermondii complex (n = 22) |
C. albicans (n = 337) |
||||||||
| GM | MIC90 | Range | GM | MIC90 | Range | GM | MIC90 | Range | |
| Micafungin | 8.28 | ≥512 | 0.25 to ≥512 | 0.27 | 1 | 0.25–4 | 0.03 | 0.031 | 0.031–1 |
| Anidulafungin | 2.46 | 232 | 0.062 to ≥512 | 1 | 2 | 0.5–1 | 0.03 | 0.031 | 0.031–0.25 |
| Fluconazole | NT | 5.27 | 16 | 0.5 to ≥64 | 0.21 | 0.25 | ≤0.125 to ≥64 | ||
| Posaconazole | NT | 0.08 | 0.5 | 0.031–1 | 0.015 | 0.015 | ≤0.015 to ≥8 | ||
| Voriconazole | NT | 0.10 | 0.5 | ≤0.015–2 | 0.016 | 0.015 | ≤0.015 to ≥8 | ||
| Amphotericin B | NT | 0.31 | 1 | 0.062–0.5 | 0.05 | 0.125 | 0.031–0.25 | ||
See reference 3. SMIC50, sessile MIC corresponding to 50% reduction of biofilm metabolic activity; GM, geometric mean; NT, not tested.