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In vitro MBEC values of colistin and CHIR-090 alone and in combination against four P. aeruginosa strains
| Strain | MBEC (μg/ml) |
ΣFICa | |
|---|---|---|---|
| Colistin | CHIR-090 | ||
| PAO1 | 256 | >128 | 0.34 (64 + 1) |
| PAO1-TJH | 512 | 64 | 0.34 (64 + 16) |
| SCV-1 | 256 | 8 | 0.13 (2 + 1) |
| SCV-2 | 256 | 128 | 0.31 (64 + 8) |
The values in parentheses are the concentrations of colistin + CHIR-090 (in micrograms per milliliter) for the reported ΣFIC values.
