FIG 2.

Population plasma concentration versus time curves for children receiving the reduced-clavulanate formulation of amoxicillin-clavulanate using various dosage regimens during phase 1 (90/3.2 mg/kg/day) and phase 2 (80/2.85 mg/kg/day). Plasma concentrations (Conc.) for time points 6, 8, 10, and 12 h were extrapolated on the basis of the elimination rate constant calculated from data collected up to 4 h. Data points up to 4 h without a standard deviation bar indicate that the assessment was available for only one child.