FIG 5.

Percent survival of mice in each treatment group following a challenge with aerosolized B. pseudomallei K96243. Mice were challenged with approximately 128 CFU of B. pseudomallei K96243 by the inhalational route and treated with oral finafloxacin (37.5 mg/kg) every 8 h, intraperitoneal ciprofloxacin (30 mg/kg) every 12 h, or oral co-trimoxazole (240 mg/kg) every 12 h. Regimens were initiated at 6 h (A) or 24 h (B) postchallenge. Control animals received intraperitoneal PBS or oral diluent. Statistical analysis was performed using the Mantel-Haenszel log rank test. *, P = 0.043; **, P = 0.004; ****, P < 0.0001.