FIG 6.

Bacterial loads in organs at 24 h following initiation of antibiotic treatment. Bacterial counts (CFU/g) in the spleens, livers, and lungs of 5 mice per group at 30 h (A) or 48 h (B) postchallenge. Each group received 24-h treatment with finafloxacin (37.5 mg/kg every 8 h orally), co-trimoxazole (240 mg/kg every 12 h orally), or ciprofloxacin (30 mg/kg every 12 h via intraperitoneal injection). Control animals received intraperitoneal PBS or oral diluent. Statistical analysis was performed using pairwise comparisons of Mood's median test. *, P < 0.05.