FIG 8.

Bacterial loads in organs at 63 days postchallenge with aerosolized B. pseudomallei. Bacterial counts (CFU/g) in the spleens, livers, and lungs of mice at day 63 postchallenge when treatment commenced at 6 h (A) or 24 h (B) postchallenge. Each group received 14 days of treatment with finafloxacin (37.5 mg/kg every 8 h orally), co-trimoxazole (240 mg/kg every 12 h orally), or ciprofloxacin (30 mg/kg every 12 h via intraperitoneal injection). Statistical analysis was performed using pairwise comparisons of Mood's median test. *, P < 0.05.