FIG 3.

Proteome response of M. tuberculosis to anti-tuberculosis drug treatments. (A) Volcano plots showing proteins that are induced or repressed by each drug across all time points. Proteins with P values of <0.05 are in blue; each dot is one protein. (B) Heat map showing the levels of proteins that were concordantly regulated across four time points by the five drugs. Raw values were log₂ transformed and normalized within each protein. The colors show relative levels as indicated by the scale bar.