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. 2017 Jun 27;61(7):e00570-17. doi: 10.1128/AAC.00570-17

FIG 2.

FIG 2

Comparative inhibitory effects of VT-1598, VT-1161, and clinical antifungal drugs on the activity of A. fumigatus CYP51B. The molar ratio of enzyme/inhibitor/substrate was 1:2:50, and the P450 concentration was 0.5 μM (60-min reaction). The experiments were performed in triplicate, and the results are presented as means ± SDs.