TABLE 1.
C. albicans strains used in this study
| Strain | Parent | Relevant characteristics or genotype | Reference or source |
|---|---|---|---|
| SC5314 | Wild-type reference strain | 46 | |
| Matched clinical isolate pairs | |||
| F2 | FLUs clinical isolate from patient F | 22 | |
| F5 | FLUr clinical isolate from patient F | 22 | |
| G2 | FLUs clinical isolate from patient G | 22 | |
| G5 | FLUr clinical isolate from patient G | 22 | |
| B3 | FLUs clinical isolate from patient B | 33 | |
| B4 | FLUr clinical isolate from patient B | 33 | |
| Gu4 | FLUs clinical isolate from patient Gu | 33 | |
| Gu5 | FLUr clinical isolate from patient Gu | 33 | |
| 1442 | FLUs clinical isolate from patient 9 | 47 | |
| 2271 | FLUr clinical isolate from patient 9 | 47 | |
| 1490 | FLUs clinical isolate from patient 40 | 47 | |
| 1587 | FLUr clinical isolate from patient 40 | 47 | |
| 5833 | FLUs clinical isolate from patient II | 48 | |
| 6692 | FLUr clinical isolate from patient II | 48 | |
| DSY294 (C43)a | FLUs clinical isolate | 49 | |
| DSY296 (C56) | FLUr clinical isolate | 49 | |
| DSY2285 (26) | FLUs clinical isolate | 50 | |
| DSY2286 (91) | FLUr clinical isolate | 50 | |
| TW1 (#1) | FLUs clinical isolate | 51 | |
| TW17 (#17) | FLUr clinical isolate | 51 | |
| RFP-labeled strains | |||
| SCADH1R1A | SC5314 | ADH1/adh1::PADH1-RFP-caSAT1 | 26 |
| F2ADH1R1A and -B | F2 | ADH1/adh1::PADH1-RFP-caSAT1 | This study |
| F5ADH1R1A and -B | F5 | ADH1/adh1::PADH1-RFP-caSAT1 | This study |
| G2ADH1R1A and -B | G2 | ADH1/adh1::PADH1-RFP-caSAT1 | This study |
| G5ADH1R1A and -B | G5 | ADH1/adh1::PADH1-RFP-caSAT1 | This study |
| B3ADH1R1A and -B | B3 | ADH1/adh1::PADH1-RFP-caSAT1 | This study |
| B4ADH1R1A and -B | B4 | ADH1/adh1::PADH1-RFP-caSAT1 | This study |
| Gu4ADH1R1A and -B | Gu4 | ADH1/adh1::PADH1-RFP-caSAT1 | This study |
| Gu5ADH1R1A and -B | Gu5 | ADH1/adh1::PADH1-RFP-caSAT1 | This study |
| 1442ADH1R1A and -B | 1442 | ADH1/adh1::PADH1-RFP-caSAT1 | This study |
| 2271ADH1R1A and -B | 2271 | ADH1/adh1::PADH1-RFP-caSAT1 | This study |
| 1490ADH1R1A and -B | 1490 | ADH1/adh1::PADH1-RFP-caSAT1 | This study |
| 1587ADH1R1A and -B | 1587 | ADH1/adh1::PADH1-RFP-caSAT1 | This study |
| 5833ADH1R1A and -B | 5833 | ADH1/adh1::PADH1-RFP-caSAT1 | This study |
| 6692ADH1R1A and -B | 6692 | ADH1/adh1::PADH1-RFP-caSAT1 | This study |
| DSY294ADH1R1A and -B | DSY294 | ADH1/adh1::PADH1-RFP-caSAT1 | This study |
| DSY296ADH1R1A and -B | DSY296 | ADH1/adh1::PADH1-RFP-caSAT1 | This study |
| DSY2285ADH1R1A and -B | DSY2285 | ADH1/adh1::PADH1-RFP-caSAT1 | This study |
| DSY2286ADH1R1A and -B | DSY2286 | ADH1/adh1::PADH1-RFP-caSAT1 | This study |
| TW1ADH1R1A and -B | TW1 | ADH1/adh1::PADH1-RFP-caSAT1 | This study |
| TW17ADH1R1A and -B | TW17 | ADH1/adh1::PADH1-RFP-caSAT1 | This study |
| Genetically engineered strains with MRR1 GOF mutations | |||
| SCMRR1R24A and -B | SC5314 | MRR1-FRT/MRR1-FRT | 26 |
| SCMRR1R34A and -B | SC5314 | MRR1P683S-FRT/MRR1P683S-FRT | 10 |
| SCMRR1R44A and -B | SC5314 | MRR1G997V-FRT/MRR1G997V-FRT | —b |
| SCMRR1R54A and -B | SC5314 | MRR1G878E-FRT/MRR1G878E-FRT | — |
| SCMRR1R64A and -B | SC5314 | MRR1Q350L-FRT/MRR1Q350L-FRT | — |
| SCMRR1R74A and -B | SC5314 | MRR1N803D-FRT/MRR1N803D-FRT | — |
| SCMRR1R84A and -B | SC5314 | MRR1T360I-FRT/MRR1T360I-FRT | — |
| SCMRR1R94A and -B | SC5314 | MRR1K335N-FRT/MRR1K335N-FRT | — |
| SCMRR1R982A and -B | SC5314 | MRR1K335N-FRT/MRR1T360I-FRT | — |
| SCMRR1R104A and -B | SC5314 | MRR1T896I-FRT/MRR1T896I-FRT | — |
| F2MRR1R34A and -B | F2 | MRR1P683S-FRT/MRR1P683S-FRT | This study |
| 5833MRR1R892A and -B | 5833 | MRR1T360I-FRT/MRR1K335N-FRT | This study |
a
Names in parentheses are previously used strain designations.
b
—, Hampe and Morschhäuser, unpublished.