FIG 3.
Structural comparison of EV71 3Cpro in the unliganded form and in complex with NK-1.8k. The structure of unliganded EV71 3Cpro (PDB accession no. 3OSY) was superimposed onto that of EV71 3Cpro in complex with NK-1.8k by using the CCP4 program. The polypeptides of EV71 3Cpro in the unliganded form or in complex with NK-1.8k are displayed as red and green cartoons, respectively. The structural elements with RMSDs of less than 0.7 Å are colored white. The bound NK-1.8k is shown as colored sticks.