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Antifungal activities of compound 14 and analogs against yeast and mold species
| Compound | MIC (μM) for growth inhibition |
||||||
|---|---|---|---|---|---|---|---|
| S. cerevisiae | C. albicans | C. parapsilosis | C. tropicalis | C. glabrata | A. fumigatus | A. flavus | |
| 14 | 7.5 | 36 | 24 | 24 | 41 | 75 | 75 |
| 15 | 1.5 | 4.8 | 15 | 47 | 15 | 15 | 24 |
| 16 | 3.2 | 15 | 15 | 28 | 11 | 15 | 47 |
| 17 | 47 | 150 | 150 | 150 | 150 | >150 | >150 |
| 18 | 24 | 75 | 24 | 58 | 41 | 75 | >75 |
| 19 | 3.7 | 6 | 3.7 | 3.7 | 3.7 | 12 | 12 |
| BM2 | 4.7 | 15 | 26 | 4.7 | 150 | >150 | >150 |
| Vanadate | >750 | >750 | >750 | >750 | >750 | >750 | >750 |
| Ebselen | 7.5 | 7.5 | 24 | 11 | 7.5 | 24 | 24 |
