Fig. 4.

Tlr-4 mRNA expression as well as 4-HNE protein adduct staining in female mice fed a C diet or WSD with or without Arg supplementation for 6 weeks. Hepatic a Tlr-4 mRNA expression as well as b densitometric analysis and c representative photomicrographs of 4-HNE protein adduct staining in the liver. Values are mean ± SEM. Means without a common letter differ, P < 0.05. NS, P ≥ 0.05. Homogeneity of the variances was not significant (P > 0.05). 4-HNE 4-hydroxynonenal; Arg arginine; C control; Tlr-4 toll-like receptor 4; WSD Western-style diet; DExAE interaction between diet and arginine, AE arginine effect, DE diet effect