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Changes in a, b MUC5AC and c, d CLCA1 mRNA expression levels, in individuals with detectable expression at baseline (day 0), after 2 days of exposure to RPC4046 (all doses). Absolute values in a, c individual patients with asthma and b, d individual healthy subjects. CLCA calcium-activated chloride channel regulator, mRNA messenger RNA, MUC5AC mucin 5AC
