Table 1.
Characteristic | Part 1 | Part 2 | Part 3 | |||
---|---|---|---|---|---|---|
Placebo (n = 4) | RPC4046 (n = 16) | Placebo (n = 3) | RPC4046 (n = 12) | Placebo (n = 4) | RPC4046 (n = 8) | |
Age, mean ± SD (years ) | 36.0 ± 13.1 | 28.1 ± 10.1 | 23.0 ± 2.0 | 33.3 ± 11.9 | 27.5 ± 8.3 | 28.8 ± 7.7 |
Weight, mean ± SD (kg) | 77.5 ± 5.8 | 78.0 ± 9.1 | 82.3 ± 11.7 | 77.8 ± 11.9 | 73.8 ± 4.5 | 79.3 ± 10.8 |
Height, mean ± SD (cm) | 176.8 ± 8.7 | 179.7 ± 6.1 | 178.0 ± 3.6 | 172.5 ± 8.2 | 173.3 ± 3.3 | 174.9 ± 6.2 |
BMI, mean ± SD (kg/m2) | 24.8 ± 1.1 | 24.2 ± 2.9 | 26.0 ± 3.9 | 26.1 ± 3.2 | 24.5 ± 0.6 | 25.9 ± 3.6 |
Male, n (%) | 4 (100) | 15 (93.8) | 3 (100) | 9 (75.0) | 4 (100) | 7 (87.5) |
White, n (%) | 2 (50.0) | 8 (50.0) | 3 (100) | 7 (58.3) | 1 (25.0) | 5 (62.5) |
Black, n (%) | 2 (50.0) | 8 (50.0) | 0 | 3 (25.0) | 2 (50.0) | 0 |
Asian, n (%) | 0 | 0 | 0 | 2 (16.7) | 1 (25.0) | 3 (37.5) |
BMI body mass index