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Regulation of pacsin’s membrane activity. Inter-dimer tip-to-tip oligomerization and membrane tubulation are reversible processes dependent on the pacsin dimer (dark and light blue moons) concentration. Phosphorylation at T181 (red circles) located at the tips of the dimers inhibits [137], whereas the presence of filamin A (FlnA) promotes [114] oligomerisation and pacsin-dependent membrane tubulation
