Figure 5.
RT‐PCR analysis of MMP‐2/ MMP‐9/MMP‐12, NGAL and IL‐6 transcripts in PBMCs from healthy and COPD smokers. (A) Representative RT‐PCR results for five samples from healthy and COPD smokers. The sample's cDNA content was normalized against the value for β2‐microglobulin. (B & C) Data are expressed as the ratio between the analyte transcript and the β2‐microglobulin transcript. Values are reported as the median (IQR). (B) Levels of MMP‐9 and NGAL transcripts in samples from healthy‐S (n = 12) and COPD‐S (n = 19) samples. (C) Levels of MMP‐9 and NGAL transcripts by GOLD stage groups (GOLD I/II, n = 14; GOLD III/IV, n = 5).