Table 3.

Genotype frequencies of nine SNPs and their association with essential hypertension risk in the Chinese population

SNPs	Controlsb	Casesb	Additive modelc		Recessive modeld
			OR (95% CI)a	P a	OR (95% CI)a	P a
rs3755278	1021/76/4	994/99/3	1.34(0.94–1.90)	0.102	1.40(0.97–2.02)	0.071
rs10206753	826/257/29	841/266/20	0.91(0.75–1.11)	0.339	0.93(0.75–1.17)	0.536
rs11685424	307/537/247	253/581/282	1.25(1.09–1.44)	0.002	1.33(1.06–1.66)	0.015
rs6543116	312/542/252	350/566/207	0.82(0.71–0.94)	0.005	0.74(0.60–0.92)	0.007
rs951774	626/408/73	661/411/55	0.92(0.78–1.08)	0.312	0.95(0.78–1.16)	0.592
rs13006559	1052/57/3	1051/79/2	1.25(0.84–1.88)	0.278	1.36(0.89–2.08)	0.158
rs12999364	437/502/169	376/560/190	1.26(1.09–1.45)	0.002	1.40(1.14–1.71)	0.001
rs3821204	478/493/134	428/540/157	1.25(1.08–1.45)	0.003	1.33(1.09–1.63)	0.005
rs13431828	921/177/11	933/183/13	0.98(0.77–1.23)	0.845	0.97(0.75–1.26)	0.827

It means P‐values <0.05 and these SNPs were significantly associated with EH.

^a P‐values were calculated by unconditional logistic regression, after adjusting for age, sex, smoking, drinking, BMI, TG, FBG and family history of EH.

^bWild‐type homozygote/heterozygote/variant homozygote.

^cAdditive model (wild‐type homozygote versus heterozygote versus variant homozygote).

^dRecessive model (wild‐type homozygote versus heterozygote + variant homozygote).