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. 2017 Apr 17;7(2):17. doi: 10.3390/bios7020017

Figure 9.

Figure 9

(A) Time dependence of normalized source-drain current of the CNT-biosensor at the source-drain bias of 0.1 V and at gate bias of 0 V after the introduction of IL-6 spiked blood sample at various concentrations onto the IL-6 aptamer functionalized CNT-biosensor. Arrows indicate the points of IL-6 spiked blood injection; (B) The Sensitivity of IL-6 aptamer CNT-biosensor as a function of IL-6 protein concentration in blood sample (10 pg to 1 ng /mL) in logarithmic scale. Diagnostic gray zone for large tumor mass at ~12–40 pg/mL is highlighted in yellow which is higher than our sensor’s lower limit sensing threshold at 10 pg/mL.