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Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
C-vine graph illustrating partial correlation structure. C-vines were utilized to generate biologically plausible metabolomics data. represents the correlation between metabolites and . represents the partial correlation between metabolites and after conditioning on and .