Abiraterone acetate fine particle is a proprietary formulation (using SoluMatrix Fine Particle Technology™) that has enhanced dissolution properties designed to increase the oral bioavailability of abiraterone acetate relative to the originator abiraterone acetate formulation.

Abiraterone acetate fine particle displayed dose proportionality over the wide range of doses (100–625 mg) tested under fasted conditions.

The 500-mg dose of abiraterone acetate fine particle was bioequivalent to the 1000-mg dose of originator abiraterone acetate based on the 90% confidence interval of the geometric mean ratio of the area under the plasma concentration–time curve and maximum plasma concentration parameters.