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. 2005 Feb;17(2):404–417. doi: 10.1105/tpc.104.028332

Figure 1.

Figure 1.

Location of Mutations of the HOG1 Gene (AT4G 13940) Coding for SAH Hydrolase.

(A) Coordinates are given in amino acids from the start of the protein. The specific amino acid change is indicated for each of the three point mutants. The positions of the insertions are indicated for the two tagged mutants. The 5′ untranslated region, 3′ untranslated region, and the unique intron (according to The Arabidopsis Information Resource [TAIR] annotation) are indicated by white boxes and exons by black boxes. The arrow indicates the direction of transcription.

(B) Partial alignment of SAH hydrolases of Arabidopsis with other eukaryotic hydrolases. The alignment is representative of hydrolases of the eukaryotic type as defined by Kurowski and Bujnicki (2003) and corresponds to the region to which the hog1 substitutions map. The substituted residues are indicated in the top row; numbering corresponds to SAH hydrolase 1. SAHH1, SAH hydrolase 1; SAHH2, SAH hydrolase 2; Dr, Danio rerio (GI 37,681,725); Rn, Rattus norvegicus (GI 38,197,378); Dm, Drosophila melanogaster (GI 7,293,098); Sc, Saccharomyces cerevisiae (GI 2,950,505); Pf, Plasmodium falciparum (GI 627050). An insertion in the D. melanogaster sequence is indicated. Invariant and highly conserved residues are highlighted.