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. 2017 Apr 28;591(11):1471–1488. doi: 10.1002/1873-3468.12652

Figure 2.

Figure 2

Sxl‐dependent alternative polyadenylation of enhancer of rudimentary mRNA. Activation of the proximal poly(A) site (proximal pA) requires the binding of CstF to a downstream RNA sequence (red). Sxl can compete with and displace CstF‐64, diverting it to a downstream site. This results in activation of a distal polyA‐site (♀ pA) and an extended 3′ UTR in female flies.