Table 2.
Frequencies of genotypes at DC-SIGN rs7252229 in NPC patients and healthy controls.
| Genotype | Cases | Controls | Unadjusted OR (95%CI) | P | Adjusted OR∗ (95%CI) | Adjusted P | P HWE |
|---|---|---|---|---|---|---|---|
| rs7252229 | 0.307 | ||||||
| CC | 8 | 1 | 1.000 | 1.000 | |||
| GC | 65 | 73 | 0.111 (0.014–0.914) | 0.041 | 0.076 (0.008–0.690) | 0.022 | |
| GG | 404 | 486 | 0.104 (0.013–0.834) | 0.033 | 0.056 (0.006–0.487) | 0.009 | |
| GC + GG | 469 | 559 | 0.105 (0.013–0.842) | 0.034 | 0.059 (0.007–0.515) | 0.010 |
∗Calculated using multiple logistic regression after controlling for age, sex, smoking history, and EBV infection factors. CI: confidence interval; DC-SIGN: dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin; HWE: Hardy-Weinberg equilibrium; NPC: nasopharyngeal carcinoma; OR: odds ratio.