Table 2.

Scope with respect to anilines^[a] and diaryliodonium salts^[b] for the meta‐selective C−H arylation in flow.

[a] Reaction conditions: 0.5 mmol aniline (5) and 2.0 equiv [Tol‐I‐Tol]OTf (4 a) in 5.0 mL DCE. [b] Reaction conditions: 0.5 mmol N‐(o‐tolyl)pivalamide (5 a) and 2.0 equiv [Ar‐I‐Mes]OTf (3) in 5.0 mL DCE. Added to the CTFR by syringe pump. [c] 40 min residence time. [d] 5.03 mmol scale reaction: 1.384 g (98 %) of desired product obtained. [e] Symmetrical [Ar‐I‐Ar]OTf (4) was used. Piv=pivaloyl.