Table 1.
Baseline Characteristics of Patients with Pseudomonas aeruginosa Infection According to Phenotype
| Characteristic | Non-MDR PA n = 37 (%) | MDR non-XDR PA n = 11 (%) | pa | XDR PA n = 13 (%) | pb |
|---|---|---|---|---|---|
| Age (mean ± SD) | 67.2 ± 12.3 | 58.9 ± 11.8 | 0.06 | 67.3 ± 17.2 | 0.98 |
| Male sex | 25 (67.6) | 9 (81.8) | 0.27 | 9 (69.2) | 0.92 |
| Days ICU-infection acquisition [median (IQT)] | 14.5 (3.75–31) | 14.5 (8.75–35.75) | 0.63 | 8.5 (3.5–15.0) | 0.21 |
| SAPS score mean (SD) | 42.0 ± 17.2 | 41.4 ± 13.0 | 0.91 | 44.3 ± 9.2 | 0.66 |
| Charlson index [median (IQT)]) | 1 (0.75–4) | 3 (2–4) | 0.18 | 2 (1.25–4) | 0.39 |
| Underlying condition | |||||
| Diabetes | 7 (19) | 1 (10) | 0.65 | 1 (8) | 0.66 |
| Chronic lung disease | 3 (8) | 3 (30) | 0.12 | 3 (23) | 0.17 |
| Heart Disease | 13 (35) | 2 (20) | 0.45 | 5 (38) | 0.83 |
| Solid malignancy | 6 (16) | 3 (30) | 0.40 | 3 (23) | 0.67 |
| Hematologic malignancy | 1 (3) | 1 (10) | 0.40 | 0 | — |
| Chronic renal failure | 3 (8) | 2 (20) | 0.31 | 1 (8) | 0.95 |
| Chronic neurologic disease | 3 (8) | 3 (30) | 0.12 | 1 (8) | 0.72 |
| Cirrhosis | 2 (5) | 3 (30) | 0.07 | 3 (23) | 0.06 |
| Neutropenia | 0 | 0 | — | 0 | — |
| Immunosuppression | 10 (27) | 1 (10) | 0.40 | 2 (15) | 0.47 |
| Outcome | |||||
| Early exitus | 6 (16) | 1 (10) | 0.56 | 1 (8) | 0.40 |
| Overall exitus | 7 (19) | 1 (10) | 0.65 | 2 (15) | 0.56 |
| Days ICU-discharge/exitus [median (IQT)] | 53 (26.5–87.25) | 59.5 (39.25–86.25) | 0.50 | 68.5 (21.0–87.75) | 0.72 |
a
Comparison of non-MDR and MDR non-XDR.
b
Comparison non-MDR and XDR.
SD, standard deviation; PA, P. aeruginosa; MDR, multidrug-resistant; XDR, extensively drug-resistant; ICU, intensive care unit; IQT, interquartile range; MODS, multiorgan dysfunction syndrome.