Table 1.
Demographic, anthropometric, and clinical data.
| Normal group | HS group | CHB group | CHB+HS group | P value | |
|---|---|---|---|---|---|
| Age (years) | 46.05 ± 6.64 | 38.98 ± 13.55 | 36.46 ± 11.93 | 39.82 ± 13.89 | <0.001 |
| Gender | M: 27 (60.00%) | M: 27 (72.97%) | M: 32 (68.09%) | M: 38 (73.08%) | 0.388 |
| F: 18 (40.00%) | F: 10 (27.03%) | F: 15 (31.91%) | F: 14 (26.92%) | ||
| BMI (kg/m2) | 23.12 ± 2.18 | 27.23 ± 3.84 | 22.59 ± 2.47 | 27.57 ± 3.35 | <0.001 |
| TC (mmol/L) | 4.26 ± 0.75 | 4.67 ± 1.30 | 4.46 ± 0.86 | 4.77 ± 0.83 | 0.021 |
| TG (mmol/L) | 1.00 ± 0.35 | 1.52 ± 0.61 | 1.15 ± 0.41 | 1.73 ± 1.29 | <0.001 |
| HDL (mmol/L) | 1.32 ± 0.24 | 1.18 ± 0.37 | 1.36 ± 0.25 | 1.19 ± 0.32 | 0.092 |
| LDL (mmol/L) | 2.32 ± 0.38 | 3.01 ± 0.62 | 2.19 ± 0.57 | 2.92 ± 0.87 | <0.001 |
| ALT (U/L) | 13.91 ± 4.00 | 50.44 ± 22.56 | 73.85 ± 52.38 | 61.19 ± 32.59 | <0.001 |
| AST (U/L) | 20.19 ± 4.84 | 27.24 ± 14.47 | 70.56 ± 49.54 | 33.74 ± 20.51 | <0.001 |
| TBIL (μmol/L) | 2.22 ± 0.42 | 4.62 ± 0.93 | 21.48 ± 14.14 | 5.86 ± 2.54 | <0.001 |
| GGT (U/L) | 15.05 ± 4.94 | 43.91 ± 20.83 | 73.79 ± 64.96 | 64.04 ± 39.57 | <0.001 |
| ALP (U/L) | 16.31 ± 4.61 | 61.58 ± 16.17 | 93.66 ± 35.80 | 89.11 ± 42.48 | <0.001 |
| Insulin (μIU/L) | 7.51 ± 1.86 | 34.37 ± 23.61 | 8.10 ± 2.37 | 30.95 ± 23.16 | <0.001 |
| HOMA-IR | 1.11 ± 0.42 | 8.25 ± 6.07 | 1.33 ± 0.42 | 7.38 ± 5.63 | <0.001 |
| FBG (mmol/L) | 3.57 ± 1.13 | 5.14 ± 1.17 | 4.15 ± 0.45 | 5.48 ± 1.83 | <0.001 |
| Hb1Ac (%) | 5.28 ± 0.97 | 5.82 ± 1.29 | 5.17 ± 1.01 | 6.12 ± 1.43 | <0.001 |
CHB: chronic hepatitis B; HS: hepatic steatosis; BMI: body mass index; TC: total cholesterol; TG: triglyceride; HDL: high-density lipoprotein; LDL: low-density lipoprotein; FBG: fasting blood glucose; ALT: alanine aminotransferase; AST: aspartate aminotransferase; TBIL: total bilirubin; GGT: γ-glutamyltransferase ALP: alkaline phosphatase; HOMA-IR: homeostasis model assessment index.