Table 1.
Candidates for novel HML-2 pre sites
Chr | Position | Region | Structure | ID | Genomes of other primatesa | Frequencyb | Total alleles | Agec (MYA) | Referenced | ||
---|---|---|---|---|---|---|---|---|---|---|---|
pre | pro | solo | |||||||||
chr3 | 195654396–195655363 | 3q29 | solo LTR | esv2668264 | ins | 0.152 | 0 | 0.848 | 46 | 2.27 | [3] |
chr4 | 120263689–120264654 | 4q26 | solo LTR | esv2661724 | ins | 0.708 | 0 | 0.292 | 48 | 2.11 | [3] |
chr7 | 16237347–16238314 | 7p21.2 | solo LTR | esv2662783 | ins | 0.5 | 0 | 0.5 | 48 | 2.42 | this study |
chr8 | 37050886–37051853 | 8p11.23 | solo LTR | esv2677273 | ins | 0.813 | 0 | 0.187 | 48 | 2.15 | this study |
chr11 | 71875418–71876385 | 11q13.4 | solo LTR | esv2675196 | ins | n.d. | n.d. | n.d. | n.d. | 2.35 | [3] |
chr6 | 3055034–3055749 | 6p25.2 | LTR+ ORF + 7bpe | esv2731485 | ins panTro4 /ponAbe2 | 0.435 | 0.565 | 0 | 46 | n.d. | this study |
aReference genomes for chimpanzee (PanTro4), gorilla (gorGor3), orangutan (PonAbe2), and rhesus macaque (rheMac8). ins: Retroviral insertion
bTested in this study; pre: preintegration, pro: provirus, solo: solo LTR, n.d. not determined
cThe previous study by Subramanian et al. was used to obtain the ages of solo LTRs [12]. MYA million years ago, n.d. not determined
dInsertional polymorphisms were inferred from the previous study by Wildschutte et al. [3].
eThe ORF was partially deleted and the flanking 7-bp sequence was assigned as part of the ORF